Best movies about serious illnesses

29 items • 98 views • 1 vote • updated Nov 7, 2026
Best movies about serious illnesses

Discover the best movies about serious illnesses, ranked from best to worst.

Based on 1 vote, the movie If I Had Legs I'd Kick You, starring Rose Byrne and Conan O'Brien, came in first as the best movie about serious illnesses, followed by 50/50 and A Walk to Remember from 2002. Scroll down for the top 10 movies about serious illnesses, recommended by movie fans in 2026.

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Recommend the best movie about serious illnesses

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If I Had Legs I'd Kick You 1
If I Had Legs I'd Kick You
2025 - Rose Byrne, Conan O'Brien, A$AP Rocky, Danielle Macdonald, Delaney Quinn, Mary...
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Linda feels that her life is falling apart: her child has a mysterious illness, her husband is absent, and the relationship with her therapist is becoming increasingly strained. Rose Byrne •••
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50/50 2
50/50
2011 - Joseph Gordon-Levitt, Seth Rogen, Anna Kendrick, Bryce Dallas Howard, Anjelica Huston...
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Inspired by a true story, a comedy centered on a 27-year-old guy who learns of his cancer diagnosis and his subsequent struggle to beat the disease.
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A Walk to Remember 3
A Walk to Remember
2002 - Mandy Moore, Shane West, Peter Coyote, Daryl Hannah, Lauren German, Clayne Crawford, Paz...
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A rebellious boy falls in love with the most innocent girl in his high school, and their love transforms them both.Drama, Romance
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Absolution 4
Absolution
2024 - Liam Neeson, Ron Perlman, Yolonda RossAction, Crime, Thriller, Mystery
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Liam Neeson plays an aging ex-boxer working as muscle for a Boston crime boss who receives an upsetting diagnosis. As his memory fades, he tries to make up for past sins, reconnect with •••
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All of a Sudden 5
All of a Sudden
2026 - Virginie Efira, Tao Okamoto, Kyōzō Nagatsuka, Kodai Kurosaki, Jean-Charles Clichet...
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Marie-Lou runs a nursing home in Paris and wants to introduce care based on listening and respect. Meeting Mari, a Japanese theater director, changes her perspective. The film directed by •••
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Awakenings 6
Awakenings
1990 - Robert De Niro, Robin Williams, John Heard, Julie Kavner, Penelope Ann Miller
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Dr. Malcolm Sayer, a shy research physician, uses an experimental drug to awaken the catatonic victims of a rare disease. Leonard is the first patient to receive the controversial •••
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Bubble Boy 7
Bubble Boy
2001 - Jake Gyllenhaal, Swoosie Kurtz, Marley SheltonComedy, Adventure, Romance
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Jimmy was born without an immune system and has spent his life inside a plastic bubble in his bedroom. When Chloe, the girl next door he loves, decides to marry her high school boyfriend •••
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Caramelo 8
Caramelo
2025 - Rafael Vitti, Amendoim, Kelzy Ecard, Arianne Botelho, Bruno Vinicius, Ademara Barros...
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Pedro, a talented chef, receives a diagnosis that changes his life. He finds hope and good humor with the help of Caramelo, a street dog who unexpectedly enters his life. Rafael Vitti •••
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Funny People 9
Funny People
2009 - Adam Sandler, Seth Rogen, Leslie MannComedy, Drama
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George Simmons, a rich and famous comedian, gives little thought to how he treats people until a doctor gives him shocking news about his health. With help from Ira, an aspiring stand-up •••
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Jack 10
Jack
1996 - Robin Williams, Diane Lane, Brian KerwinComedy, Family, Drama
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Because of a rare condition, Jack Powell grows four times faster than other children: at ten, he looks like a forty-year-old man. After years of homeschooling, he goes to a public school •••
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Frequently asked questions

Which movie is in first place?

If I Had Legs I'd Kick You is currently ranked first on TopFaves, with 1 vote for and 0 votes against in this list.

What are the top three spots?

The top three spots are held, in order, by If I Had Legs I'd Kick You, 50/50, A Walk to Remember. The ranking can change as votes are added.

What are the most recent movies in this list?

Among the titles with a known release year, the most recent are: All of a Sudden (2026), The Debt Collector (2026), The Last Sunrise (2026).

Which movies from 2000–2009 are included?

Titles released in this period include Funny People (2009), The Bucket List (2007), The Fountain (2006).

How many votes have been recorded?

In total, 1 vote has been recorded. The total refers to the whole list and is not the number of different people who voted.

How do I vote and how is the ranking decided?

Press the up arrow if you recommend an option or the down arrow if you do not. You can use the search box in the list to quickly find a name and vote directly. The order takes into account both positive and negative votes and how many there are, and positions can change as votes are added.